Article
A note on including phenotypic information from monozygotic twins in variance components QTL linkage analysis.
Annals of human genetics - 1 Nov 2003
Evans D M, Medland S E
Abstract excerpt
Williams & Blangero (1999) derived closed form expressions for the power of a univariate variance components test of linkage for a variety of pedigree structures. We have extended their results by investigating the effect of including monozygotic twins in the design on the power to detect linkage. Specifically, we determined the power associated with a pedigree of size three, where individuals one and two were...
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