Article
Identifying the phenotypic effect of rare variants by including between-pedigree coancestry in variance components linkage analysis
2017-11-07
Abstract excerpt
The contribution of rare variants to disease burden has become an important focus in genetic epidemiology. These effects are difficult to detect in population-based datasets, and as a result, interest in family-based study designs has resurfaced. Linkage analysis tools will need to be updated to accommodate the scale of data generated by modern genotyping and sequencing technologies. In conventional linkage analys...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- b08d2753-3034-5408-af34-eca02a95ac6e
- DOI
- 10.1101/215863