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Article

SNP analysis of genes implicated in T cell proliferation in primary biliary cirrhosis.

Clinical & developmental immunology - 1 Dec 2005

Oertelt Sabine, Kenny Thomas P, Selmi Carlo, Invernizzi Pietro, Podda Mauro, Gershwin M Eric

Abstract excerpt

Previous studies on primary biliary cirrhosis (PBC) have focused on the role of T lymphocytes as potential effectors of tissue injury. We hypothesized that single nucleotide polymorphisms (SNPs) of genes involved in lymphocyte proliferation would be responsible for uncontrolled expansion of T cells and autoreactivity. To address this, we genotyped DNA from 154 patients with PBC and 166 ethnically matched healthy...

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Share to Antigens, Differentiation, T-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to CTLA-4 Antigen

Share to Inducible T-Cell Co-Stimulator Protein

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Source

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Identifiers

PMID: 16584111
DOI: 10.1080/17402520500317859
PMCID: PMC2270736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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