Article
STAT4 gene polymorphisms are associated with susceptibility and ANA status in primary biliary cirrhosis.
Disease markers - 1 Jan 2014
Joshita Satoru, Umemura Takeji, Nakamura Minoru, Katsuyama Yoshihiko, Shibata Soichiro, Kimura Takefumi, Morita Susumu, Komatsu Michiharu, Matsumoto Akihiro, Yoshizawa Kaname, Ishibashi Hiromi, Tanaka Eiji, Ota Masao
Abstract excerpt
Recent genome-wide association studies suggest that genetic factors contribute to primary biliary cirrhosis (PBC) susceptibility. Although several reports have demonstrated that the interleukin (IL) 12 signaling pathway is involved in PBC pathogenesis, its precise genetic factors have not been fully clarified. Here, we performed an association analysis between IL12A, IL12RB, and signal transducer and activator of...
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