Article
Cytotoxic T-lymphocyte antigen 4 gene +49A/G polymorphism significantly associated with susceptibility to primary biliary cirrhosis: a meta-analysis.
Journal of digestive diseases - 1 Dec 2011
Chen Rui Rui, Han Zhe Yi, Li Jin Ge, Shi Yong Quan, Zhou Xin Min, Wang Jing Bo, Cai Xi Qiang, Wang Xue Chang, Han Ying, Fan Dai Ming
Abstract excerpt
OBJECTIVE: To evaluate comprehensively the association of cytotoxic T-lymphocyte antigen 4 (CTLA-4) +49A/G polymorphism with susceptibility to primary biliary cirrhosis (PBC). METHODS: PubMed was used to search for the relevant published articles. The risk of PBC association with the CTLA-4+49A/G polymorphism was estimated for each study in a random-effects model. Odds ratio (OR) and 95% confidence interval (CI)...
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