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Article

Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients.

Journal of hepatology - 1 Sept 2010

Joshita Satoru, Umemura Takeji, Yoshizawa Kaname, Katsuyama Yoshihiko, Tanaka Eiji, Nakamura Minoru, Ishibashi Hiromi, Ota Masao

Abstract excerpt

BACKGROUND & AIMS: Primary biliary cirrhosis (PBC) is an organ-specific autoimmune disease of still unidentified genetic etiology that is characterized by chronic inflammation of the liver. Since cytotoxic T-lymphocyte antigen 4 (CTLA4) polymorphisms have recently been linked with PBC susceptibility in studies on Caucasians, we investigated the genetic association between CTLA4 polymorphisms and PBC in a Japanese...

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Source

Identifiers

PMID: 20557968
DOI: 10.1016/j.jhep.2010.03.017

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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