Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients.

doi:10.1007/s00535-011-0417-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients.

Journal of gastroenterology - 1 Oct 2011

Aiba Yoshihiro, Nakamura Minoru, Joshita Satoru, Inamine Tatsuo, Komori Atsumasa, Yoshizawa Kaname, Umemura Takeji, Horie Hitomi, Migita Kiyoshi, Yatsuhashi Hiroshi, Nakamuta Makoto, Fukushima Nobuyoshi, Saoshiro Takeo, Hayashi Shigeki, Kouno Hiroshi, Ota Hajime, Muro Toyokichi, Watanabe Yukio, Nakamura Yoko, Komeda Toshiki, Shimada Masaaki, Masaki Naohiko, Komatsu Tatsuji, Yagura Michiyasu, Sugi Kazuhiro, Koga Michiaki, Tsukamoto Kazuhiro, Tanaka Eiji, Ishibashi Hiromi

Abstract excerpt

BACKGROUND: Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis (PBC). In order to dissect the genetic basis for the production of these autoantibodies, as well as the development and progression of PBC in Japanese patients, we examined single nucleotide polymorphisms (SNPs) in cytotoxic T-lymphocyte antigen 4 (CTLA4) and solute carrier family 4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anion Transport Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antiporters

Share to Autoantibodies

Share to Centromere

Share to Chloride-Bicarbonate Antiporters

Share to CTLA-4 Antigen

Share to Liver Cirrhosis, Biliary

Share to Nuclear Pore Complex Proteins

Source

Open in PubMed

Identifiers

PMID: 21594562
DOI: 10.1007/s00535-011-0417-7

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients.PMID 21594562Read ↗

Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients.Semantic proximity Read ↗

Cytotoxic T-lymphocyte associated antigen-4 gene polymorphisms and primary biliary cirrhosis: a systematic review.Semantic proximity Read ↗

Genetic Polymorphisms of Cytotoxic T-Lymphocyte Antigen 4 in Primary Biliary Cholangitis: A Meta-Analysis.Semantic proximity Read ↗

Analysis of HLA‐DRB1 polymorphisms in Japanese patients with primary biliary cirrhosis (PBC): The HLA‐DRB1polymorphism determines the relative risk of antinuclear antibodies for disease progression in PBCSemantic proximity Read ↗

Association between cytotoxic T-lymphocyte antigen 4 gene polymorphisms and primary biliary cirrhosis in Chinese population: data from a multicenter study.Semantic proximity Read ↗

A2BP1 as a novel susceptible gene for primary biliary cirrhosis in Japanese patients.Semantic proximity Read ↗

Human leukocyte antigen class II molecules confer both susceptibility and progression in Japanese patients with primary biliary cirrhosis.Semantic proximity Read ↗

Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosisSemantic proximity Read ↗

Genetic architecture of primary biliary cholangitis: strong evidence for HLA and non-HLA risk lociSemantic proximity Read ↗

Primary biliary cirrhosis is associated with a genetic variant in the 3' flanking region of the CTLA4 gene.Semantic proximity Read ↗

What is new in primary biliary cirrhosis?Semantic proximity Read ↗

Possible association of cytotoxic T lymphocyte antigen-4 genetic polymorphism with liver damage of primary biliary cirrhosis in Japan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.