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Article

Cytotoxic T-lymphocyte-associated antigen-4 single nucleotide polymorphisms and haplotypes in primary biliary cirrhosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Jun 2007

Donaldson Peter, Veeramani Sivakumar, Baragiotta Anna, Floreani Annarosa, Venturi Carla, Pearce Simon, Wilson Valerie, Jones David, James Oliver, Taylor John, Newton Julia, Bassendine Margaret

Abstract excerpt

BACKGROUND & AIMS: Twin and family studies suggest that there is a significant heritable component to primary biliary cirrhosis (PBC). Selected cytotoxic T-lymphocyte-associated antigen-4 (CTLA4) gene polymorphisms have been proposed as nonspecific determinants of disease risk in a variety of autoimmune diseases, including PBC. However, there has been considerable debate over the validity of these associations...

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Source

Identifiers

PMID: 17482523
DOI: 10.1016/j.cgh.2007.02.012

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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