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Article

Common genetic variation and haplotypes of the anion exchanger SLC4A2 in primary biliary cirrhosis.

The American journal of gastroenterology - 1 Jun 2009

Juran Brian D, Atkinson Elizabeth J, Larson Joseph J, Schlicht Erik M, Lazaridis Konstantinos N

Abstract excerpt

OBJECTIVES: Deficiencies of the anion exchanger SLC4A2 are thought to play a pathogenic role in primary biliary cirrhosis (PBC), as the evidenced by decreased expression and activity in PBC patients and development of disease features in SLC4A2 knockout mice. We hypothesized that genetic variation in SLC4A2 might influence this pathogenic contribution. Thus, we aimed to perform a comprehensive assessment of...

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Identifiers

PMID: 19491853
DOI: 10.1038/ajg.2009.103
PMCID: PMC2853916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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