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Article

Overlapping BXSB congenic intervals, in combination with microarray gene expression, reveal novel lupus candidate genes.

Genes and immunity - 1 Apr 2006

Haywood M E K, Rose S J, Horswell S, Lees M J, Fu G, Walport M J, Morley B J

Abstract excerpt

The BXSB mouse strain is an important model of glomerulonephritis observed in systemic lupus erythematosus (SLE). Linkage studies have successfully identified disease-susceptibility intervals; however, extracting the identity of the susceptibility gene(s) in such regions is the crucial next step. Congenic mouse strains present a defined genetic resource that is highly amenable to microarray analysis. We have...

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PMID: 16541099
DOI: 10.1038/sj.gene.6364294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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