Article
Susceptibility genes in the pathogenesis of murine lupus.
Arthritis research - 1 Jan 2002
Nguyen Charles, Limaye Nisha, Wakeland Edward K
Abstract excerpt
Systemic lupus erythematosus (SLE) is the paradigm of a multisystem autoimmune disease in which genetic factors strongly influence susceptibility. Through genome scans and congenic dissection, numerous loci associated with lupus susceptibility have been defined and the complexity of the inheritance of this disease has been revealed. In this review, we provide a brief description of animal models of SLE, both...
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