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Article

Genome-wide and species-wide dissection of the genetics of arthritis severity in heterogeneous stock mice.

Arthritis and rheumatism - 1 Sept 2011

Johnsen Alyssa K, Valdar William, Golden Louis, Ortiz-Lopez Adriana, Hitzemann Robert, Flint Jonathan, Mathis Diane, Benoist Christophe

Abstract excerpt

OBJECTIVE: Susceptibility to inflammatory arthritis is determined by a complex set of environmental and genetic factors, but only a portion of the genetic effect can be explained. Conventional genome-wide screens of arthritis models using crosses between inbred mice have been hampered by the low resolution of results and by the restricted range of natural genetic variation sampled. The aim of this study was to...

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Source

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Identifiers

PMID: 21560115
DOI: 10.1002/art.30425
PMCID: PMC3371645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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