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Article

Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus.

Immunity - 1 Sept 2001

Rozzo S J, Allard J D, Choubey D, Vyse T J, Izui S, Peltz G, Kotzin B L

Abstract excerpt

The Nba2 locus is a major genetic contribution to disease susceptibility in the (NZB x NZW)F(1) mouse model of systemic lupus. We generated C57BL/6 mice congenic for this NZB locus, and these mice produced antinuclear autoantibodies characteristic of lupus. F(1) offspring of congenic and NZW mice...

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Source

Identifiers

PMID: 11567633
DOI: 10.1016/s1074-7613(01)00196-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11567633-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus.PMID 11567633Read ↗

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Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein.Semantic proximity Read ↗

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