Functional dissection of systemic lupus erythematosus using congenic mouse strains.

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Article

Functional dissection of systemic lupus erythematosus using congenic mouse strains.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 1997

Morel L, Mohan C, Yu Y, Croker B P, Tian N, Deng A, Wakeland E K

Abstract excerpt

We describe the in vivo phenotypes associated with three genomic intervals containing systemic lupus erythematosus (SLE)-susceptibility genes derived from the SLE-prone NZM2410 strain on a C57BL/6 genome. These intervals were identified previously via a genome-wide analysis of SLE susceptibility...

Topics

Animals
Antibodies, Antinuclear
B-Lymphocytes
Cell Lineage
Genetic Predisposition to Disease
Immunoglobulin G
Immunoglobulin M
Lupus Erythematosus, Systemic
Lupus Nephritis
Mice
Mice, Inbred C57BL
Mice, Inbred NZB
Phenotype
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 9190957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9190957-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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