Article
A genetic analysis of lupus.
Allergy - 1 Jan 2002
Theofilopoulos A N, Kono D H
Abstract excerpt
Systemic lupus erythematosus (SLE) is a complex multigenic inherited disease with susceptibility determined by a combination of genetic, environmental and stochastic factors. Although not yet defined, recent technical advances have provided the means to dissect the component genetic contributions of polygenic traits. We have applied such approaches to mouse models of spontaneous SLE and, in this report, summarize...
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