Multiple lupus susceptibility loci map to chromosome 1 in BXSB mice.

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Article

Multiple lupus susceptibility loci map to chromosome 1 in BXSB mice.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 1998

Hogarth M B, Slingsby J H, Allen P J, Thompson E M, Chandler P, Davies K A, Simpson E, Morley B J, Walport M J

Abstract excerpt

BXSB mice spontaneously develop a lupus-like syndrome that is accelerated by the Yaa gene (Y-linked autoimmune accelerator). We studied the phenotype of disease in (B10 x BXSB)F1 and (BXSB x (B10 x BXSB)F1) backcross mice and genotyped 224 backcross animals to allow a microsatellite-based genome-...

Topics

Animals
Autoantibodies
Chromosome Mapping
Crosses, Genetic
Disease Susceptibility
Genetic Linkage
Genetic Markers
Kidney
Lupus Nephritis
Lymph Nodes
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Phenotype
Spleen

Source

Open in PubMed

Identifiers

PMID: 9743333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9743333-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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