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Article

Multiple lupus susceptibility loci map to chromosome 1 in BXSB mice.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 1998

Hogarth M B, Slingsby J H, Allen P J, Thompson E M, Chandler P, Davies K A, Simpson E, Morley B J, Walport M J

Abstract excerpt

BXSB mice spontaneously develop a lupus-like syndrome that is accelerated by the Yaa gene (Y-linked autoimmune accelerator). We studied the phenotype of disease in (B10 x BXSB)F1 and (BXSB x (B10 x BXSB)F1) backcross mice and genotyped 224 backcross animals to allow a microsatellite-based genome-wide linkage analysis to be conducted. In the backcross population, three intervals on chromosome 1 showed significant...

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PMID: 9743333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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