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Article

p16 gene alterations in locally advanced squamous cell carcinoma of the head and neck.

Oncology reports - 1 Mar 2006

Wang Dian, Grecula John C, Gahbauer Reinhard A, Schuller David E, Jatana Kris R, Biancamano John D, Lang James C

Abstract excerpt

We previously documented the presence of mutations/deletions in the tumor suppressor gene p16 in squamous cell carcinoma of the head and neck (SCCHN). However, the association of these p16 alterations with clinical outcome is unknown. In this study, RNA was isolated from 19 frozen SCCHN from 19 patients who were previously enrolled in the OSU intensification regimen 2. Quantitative real-time RT-PCR and direct...

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PMID: 16465427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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