Article
p16 and p53 Protein expression as prognostic indicators of survival and disease recurrence from head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2002
Geisler Stacy A, Olshan Andrew F, Weissler Mark C, Cai Jainwen, Funkhouser William K, Smith Joanna, Vick Katie
Abstract excerpt
PURPOSE: Markers of somatic mutation such as p16 and p53 remain controversial prognostic indicators for patients with squamous cell carcinoma of the head and neck (SCCHN). The relationship between p53 protein expression and radiation therapy is also unclear. EXPERIMENTAL DESIGN: We made a prospective cohort study (n = 171) of incident cases receiving standardized therapy for SCCHN. RESULTS: Patients whose tumors...
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