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Article

Novel Pol II fusion promoter directs human immunodeficiency virus type 1-inducible coexpression of a short hairpin RNA and protein.

Journal of virology - 1 Feb 2006

Unwalla Hoshang J, Li Hai-Tang, Bahner Ingrid, Li Ming-Jie, Kohn Donald, Rossi John J

Abstract excerpt

We demonstrate a novel approach for coexpression of a short hairpin RNA (shRNA) with an open reading frame which exploits transcriptional read-through of a minimal polyadenylation signal from a Pol II promoter. We first observed efficient inducible expression of enhanced green fluorescent protein along with an anti-rev shRNA. We took advantage of this observation to test coexpression of the transdominant negative...

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Identifiers

PMID: 16439542
DOI: 10.1128/JVI.80.4.1863-1873.2006
PMCID: PMC1367144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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