Article
Exogenous peptide and protein expression levels using retroviral vectors in human cells.
Molecular therapy : the journal of the American Society of Gene Therapy - 1 Nov 2001
Sandrock T M, Risley B, Richards B T, Poritz M A, Austin H A, Yoo S, Kim M K, Roth B, Repetny K, Hsu F, Stump M, Teng D H, Kamb A
Abstract excerpt
Pseudotyped retroviral vectors combine the advantages of broad host range, high expression, stable chromosomal integration, and ease of preparation. These vectors greatly facilitate delivery into mammalian cells of sequences encoding individual peptide inhibitors-including those with therapeutic utility-and inhibitor libraries. However, retroviral vectors vary in behavior, particularly with respect to expression...
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