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Article

A multiplexed miRNA and transgene expression platform for simultaneous repression and expression of protein coding sequences.

Molecular bioSystems - 1 Jan 2016

Seyhan Attila A

Abstract excerpt

Knockdown of single or multiple gene targets by RNA interference (RNAi) is necessary to overcome escape mutants or isoform redundancy. It is also necessary to use multiple RNAi reagents to knockdown multiple targets. It is also desirable to express a transgene or positive regulatory elements and inhibit a target gene in a coordinated fashion. This study reports a flexible multiplexed RNAi and transgene platform...

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Identifiers

PMID: 26617199
DOI: 10.1039/c5mb00506j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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