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Article

Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients.

Journal of human genetics - 1 Jan 2006

Mushiroda Taisei, Ohnishi Yozo, Saito Susumu, Takahashi Atsushi, Kikuchi Yuka, Saito Shigeru, Shimomura Hideki, Wanibuchi Yasuhiko, Suzuki Takao, Kamatani Naoyuki, Nakamura Yusuke

Abstract excerpt

Warfarin is the most commonly used oral anticoagulant for treatment of thromboembolism, but adjustment of the dose appropriate to each patient is not so easy because of the large inter-individual variation in dose requirement. We analyzed single nucleotide polymorphism (SNP) genotypes of the VKORC1 and CYP2C9 genes using DNA from 828 Japanese patients treated with warfarin, and investigated association between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16432637
DOI: 10.1007/s10038-005-0354-5

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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