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Article

Effect of VKORC1-1639 G>A polymorphism, body weight, age, and serum albumin alterations on warfarin response in Japanese patients.

Thrombosis research - 1 Jun 2009

Yoshizawa Misa, Hayashi Hideki, Tashiro Yoshio, Sakawa Sonoko, Moriwaki Hideaki, Akimoto Takehide, Doi Osamu, Kimura Midori, Kawarasaki Yoshinori, Inoue Kazuyuki, Itoh Kunihiko

Abstract excerpt

INTRODUCTION: To establish individualized warfarin therapy, we investigated the contribution of genetic variations of vitamin K epoxide reductase complex subunit 1 gene (VKORC1) -1639 G>A and Cytochrome P450 2C9 gene (CYP2C9) and clinical factors on warfarin sensitivity in Japanese patients. MATERIALS AND METHODS: Genetic analyses of VKORC1 -1639 G>A and CYP2C9 2, 3, and 4 were performed in 259 Japanese patients...

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Source

Identifiers

PMID: 19135231
DOI: 10.1016/j.thromres.2008.11.011

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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