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Article

Proposal of pharmacogenetics-based warfarin dosing algorithm in Korean patients.

Journal of human genetics - 1 Apr 2011

Choi Jung Ran, Kim Jeong-Oh, Kang Dae Ryong, Yoon Seong-Ae, Shin Jung-Young, Zhang XiangHua, Roh Mee Ork, Hong Hyung Joo, Wang Young-Pil, Jo Keon-Hyon, Lee Kwang-Soo, Yun Ho-Jung, Oh Yong-Seog, Yoo Ki-Dong, Jeon Hee-Gyeong, Lee Yoon Sook, Kang Tae Sun, Park Hyun-Joo, Chung Myeon Woo, Kang Jin-Hyoung

Abstract excerpt

Warfarin is a commonly prescribed anticoagulant drug for the prevention of thromboembolic disorders. We investigated the contribution of genetic variations of four genes and clinical factors to warfarin dose requirement and provided a warfarin-dosing algorithm based on genetic and clinical variables in Korean patients. We recruited 564 Korean patients on stable anticoagulation. Single nucleotide polymorphisms...

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Source

Identifiers

PMID: 21326313
DOI: 10.1038/jhg.2011.4

Genes

VKORC1
GGCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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