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Article

Extremely low warfarin dose in patients with genotypes of CYP2C93/3 and VKORC1-1639A/A.

Chinese medical journal - 1 Sept 2011

Gao Lei, He Lei, Luo Jin, Xu Bin, Yang Jie, Zhang Yu-xiao, Yang Ting, Li Ke, Tian Jin-wen, Wang Hong-juan, Zhao Yu-sheng, Lu Cai-yi, Zhang Wen-zi, Yin Tong

Abstract excerpt

BACKGROUND: Patients with the genotypes of both CYP2C9*3/*3 and VKORC1-1639 A/A are expected to require the lowest dose of warfarin, and to have a greatly increased risk of bleeding. The experience for the dosing of warfarin in such extremely rare cases has been seldom reported. METHODS: Demographic and clinical data from two cases with stable low dose of warfarin in China were studied by resequencing the...

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Source

Identifiers

PMID: 22040439

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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