Article
The Legionella pneumophila global regulatory protein LetA affects DotA and Mip.
International journal of medical microbiology : IJMM - 1 Feb 2006
Shi Chunwei, Forsbach-Birk Vera, Marre Reinhard, McNealy Tamara L
Abstract excerpt
Several genes have been identified in Legionella pneumophila which are necessary for its virulence properties. These genes include the dot/icm type IV secretion system (T4SS), mip and letA. Genes of the dot/icm system, in particular dotA, have been found to be essential for intracellular growth. The macrophage infectivity protein (Mip) is also necessary for full virulence of the bacteria. Although these genes are...
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