Article
The LetE protein enhances expression of multiple LetA/LetS-dependent transmission traits by Legionella pneumophila.
Infection and immunity - 1 Jun 2004
Bachman Michael A, Swanson Michele S
Abstract excerpt
Legionella pneumophila colonizes freshwater amoebae and can also replicate within alveolar macrophages. When their nutrient supply is exhausted, replicating bacteria become cytotoxic, motile, and infectious, which is thought to promote transmission to a new amoeba. The differentiation of L. pneumophila is coordinated by the sigma factors RpoS and FliA and the two-component regulator LetA/LetS and is enhanced by...
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