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The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii.

Molecular microbiology - 1 Mar 2007

Zusman Tal, Aloni Gali, Halperin Einat, Kotzer Hani, Degtyar Elena, Feldman Michal, Segal Gil

Abstract excerpt

Legionella pneumophila and Coxiella burnetii have been shown to utilize the icm/dot type IV secretion system for pathogenesis and recently a large number of icm/dot-translocated substrates were identified in L. pneumophila. Bioinformatic analysis has revealed that 13 of the genes encoding for L. pneumophila-translocated substrates and five of the C. burnetii icm/dot genes, contain a conserved regulatory element...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17302824
DOI: 10.1111/j.1365-2958.2007.05604.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii.PMID 17302824Read ↗

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Additive effect on intracellular growth by Legionella pneumophila Icm/Dot proteins containing a lipobox motif.Semantic proximity Read ↗

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Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for <i>Legionella pneumophila</i> intracellular growthSemantic proximity Read ↗

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