Article
Helicobacter pylori CagA transfection of gastric epithelial cells induces interleukin-8.
Cellular microbiology - 1 Jan 2006
Kim Seok-Yong, Lee Yong-Chan, Kim Hyong Kyu, Blaser Martin J
Abstract excerpt
To determine the effect of Helicobacter pylori CagA expression on interleukin-8 (IL-8) induction in AGS cells, cagA and five of its fragments from strains 147A and 147C that vary in the 3' repeat region were cloned into the eukaryotic expression plasmid pSP65SRalpha. IL-8, but not RANTES or IL-Ibeta, levels were increased in AGS cells transfected with 147A-cagA and to a greater extent with 147C-cagA, compared...
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