Article
Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection.
Proceedings of the National Academy of Sciences of the United States of America - 12 Nov 2002
Guillemin Karen, Salama Nina R, Tompkins Lucy S, Falkow Stanley
Abstract excerpt
Helicobacter pylori infects over half the world's population and causes a wide range of diseases, including gastritis, peptic ulcer, and two forms of gastric cancer. H. pylori infection elicits a variety of phenotypic responses in cultured gastric epithelial cells, including the expression of proinflammatory genes and changes in the actin cytoskeleton. Both of these responses are mediated by the type IV secretion...
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