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Activation of IL-8 Gene Expression by <i>Helicobacter pylori</i> Is Regulated by Transcription Factor Nuclear Factor-κB in Gastric Epithelial Cells

1998-03-01

Abstract excerpt

Abstract In vivo, gastric infection with Helicobacter pylori leads to substantial production of the inflammatory cytokines IL-1, IL-6, TNF-α, and IL-8. H. pylori strains that contain the cag pathogenicity island (cag+) and are associated with ulceration and gastric carcinoma induce greater cytokine production than cag− strains. Expression of these cytokines is often regulated by the transcription factor complex, n...

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Literature Corpus work
cc339e3c-f2d8-526f-a995-8fb383813ef4
DOI
10.4049/jimmunol.160.5.2401
Open publication

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Activation of IL-8 Gene Expression by <i>Helicobacter pylori</i> Is Regulated by Transcription Factor Nuclear Factor-κB in Gastric Epithelial CellsDOI 10.4049/jimmunol.160.5.2401
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