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Article

Regulation of interleukin-6 promoter activation in gastric epithelial cells infected with Helicobacter pylori.

Molecular biology of the cell - 1 Oct 2005

Lu Hong, Wu Jeng Yih, Kudo Takahiko, Ohno Tomoyuki, Graham David Y, Yamaoka Yoshio

Abstract excerpt

The regulation of Helicobacter pylori induced interleukin (IL)-6 in the gastric epithelium remains unclear. Primary gastric epithelial cells and MKN28 cells were cocultured with H. pylori and its isogenic cag pathogenicity island (PAI) mutant and/or oipA mutants. H. pylori infection-induced IL-6 mRNA expression and IL-6 protein production, which was further enhanced by the cag PAI and OipA. Luciferase reporter...

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Identifiers

PMID: 16030249
DOI: 10.1091/mbc.e05-05-0426
PMCID: PMC1237095

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EBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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