Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro.

doi:10.1128/iai.63.5.1681-1687.1995

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Article

Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro.

Infection and immunity - 1 May 1995

Sharma S A, Tummuru M K, Miller G G, Blaser M J

Abstract excerpt

Gastric infection with Helicobacter pylori activates a mucosal inflammatory response by mononuclear cells and neutrophils that includes expression of cytokines interleukin-1 beta (IL-1 beta), IL-6, tumor necrosis factor alpha, and IL-8. In this study, we analyzed the IL-8 response of human gastric cancer cell lines (Kato III, AGS, and MKN28) to H. pylori infection in vitro. IL-8 mRNA expression was detected by...

Topics

Antigens, Bacterial
Bacterial Proteins
Bacterial Toxins
Base Sequence
Cytotoxins
Epithelium
Gastric Mucosa
Gene Expression
Helicobacter pylori
Humans
Interleukin-8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

RNA, Messenger

Species Specificity

Stomach Neoplasms

Tissue Distribution

Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 7729872
DOI: 10.1128/iai.63.5.1681-1687.1995
PMCID: PMC173210

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7729872-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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