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Article

High frequency induction of mitotic recombination by ionizing radiation in Mlh1 null mouse cells.

Mutation research - 22 Feb 2006

Wang Qi, Ponomareva Olga N, Lasarev Michael, Turker Mitchell S

Abstract excerpt

Mitotic recombination in somatic cells involves crossover events between homologous autosomal chromosomes. This process can convert a cell with a heterozygous deficiency to one with a homozygous deficiency if a mutant allele is present on one of the two homologous autosomes. Thus mitotic recombination often represents the second mutational step in tumor suppressor gene inactivation. In this study we examined the...

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Identifiers

PMID: 16343558
DOI: 10.1016/j.mrfmmm.2005.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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