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Article

Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells.

Mutation research - 1 Oct 2011

Denissova Natalia G, Tereshchenko Irina V, Cui Eric, Stambrook Peter J, Shao Changshun, Tischfield Jay A

Abstract excerpt

Maintenance of genomic integrity in embryonic cells is pivotal to proper embryogenesis, organogenesis and to the continuity of species. Cultured mouse embryonic stem cells (mESCs), a model for early embryonic cells, differ from cultured somatic cells in their capacity to remodel chromatin, in their repertoire of DNA repair enzymes, and in the regulation of cell cycle checkpoints. Using 129XC3HF1 mESCs...

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Share to Adenine Phosphoribosyltransferase
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21802432
DOI: 10.1016/j.mrfmmm.2011.06.017
PMCID: PMC3172342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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