Gene mutation and V(D)J recombination in the radiosensitive irs lines.

doi:10.1093/mutage/9.2.163

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Article

Gene mutation and V(D)J recombination in the radiosensitive irs lines.

Mutagenesis - 1 Mar 1994

Thacker J, Ganesh A N, Stretch A, Benjamin D M, Zahalsky A J, Hendrickson E A

Abstract excerpt

The lines irs1, irs2 and irs3, derived from V79-4 hamster cells, are sensitive to DNA-damaging agents including ionizing radiations. However, unlike some other radiosensitive lines, the irs lines show no apparent defect in the repair of DNA strand breaks. We have now assessed the mis-repair of DN...

Topics

Animals
Base Sequence
Cell Line
Cell Survival
Cricetinae
Cricetulus
DNA
DNA Repair
Drug Resistance
Gene Rearrangement, B-Lymphocyte
Genes
Hypoxanthine Phosphoribosyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lung

Molecular Sequence Data

Mutagenesis

Mutagenicity Tests

Mutation

Oligonucleotide Probes

Source

Open in PubMed

Identifiers

PMID: 8201950
DOI: 10.1093/mutage/9.2.163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8201950-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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