Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The glucocorticoid-induced tumor necrosis factor receptor-related gene modulates the response to Candida albicans infection.

Infection and immunity - 1 Nov 2005

Agostini Massimiliano, Cenci Elio, Pericolini Eva, Nocentini Giuseppe, Bistoni Giovanni, Vecchiarelli Anna, Riccardi Carlo

Abstract excerpt

The glucocorticoid-induced tumor necrosis factor (TNF) receptor-related gene (GITR; TNFRSF18) modulates immune response activating coaccessory signals in T cells and is expressed at high levels in CD4+CD25+ cells. Its ligand (GITRL) is expressed in antigen-presenting cells, where it is capable of promoting signaling. We investigated the role of GITR/GITRL interaction during disseminated candidiasis in GITR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candidiasis
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-12

Share to Lymphocyte Activation

Share to Receptors, Nerve Growth Factor

Share to Receptors, Tumor Necrosis Factor

Share to Sequence Homology, Amino Acid

Share to T-Lymphocyte Subsets

Source

Open in PubMed Open full text

Identifiers

PMID: 16239552
DOI: 10.1128/IAI.73.11.7502-7508.2005
PMCID: PMC1273911

Genes

TNF
TNFRSF18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The glucocorticoid-induced tumor necrosis factor receptor-related gene modulates the response to Candida albicans infection.PMID 16239552Read ↗

Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.Semantic proximity Read ↗

Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis.Semantic proximity Read ↗

Reciprocal regulation of IL‐23 and IL‐12 following co‐activation of Dectin‐1 and TLR signaling pathwaysSemantic proximity Read ↗

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in miceSemantic proximity Read ↗

Disruption of Glucocorticoid Action on CD11c+ Dendritic Cells Favors the Generation of CD4+ Regulatory T Cells and Improves Fetal Development in Mice.Semantic proximity Read ↗

TRAF4 functions as an intermediate of GITR-induced NF-kappaB activation.Semantic proximity Read ↗

Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection.Semantic proximity Read ↗

Coculture of THP‐1 Human Mononuclear Cells with<i>Candida albicans</i>Results in Pronounced Changes in Host Gene ExpressionSemantic proximity Read ↗

The Y238X stop codon polymorphism in the human β-glucan receptor dectin-1 and susceptibility to invasive aspergillosis.Semantic proximity Read ↗

Tissue glucocorticoid resistance/hypersensitivity syndromes.Semantic proximity Read ↗

Aberrant GITR expression on different T cell subsets and the regulation by glucocorticoid in systemic lupus erythematosus.Semantic proximity Read ↗

Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.