Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection.

JCI insight - 3 May 2018

Ramani Kritika, Jawale Chetan V, Verma Akash H, Coleman Bianca M, Kolls Jay K, Biswas Partha S

Abstract excerpt

Kidney injury is a frequent outcome in patients with disseminated Candida albicans fungal infections. IL-17 receptor (IL-17R) signaling is critical for renal protection against disseminated candidiasis, but the identity and function of IL-17-responsive cells in mediating renal defense remains an active area of debate. Using BM chimeras, we found that IL-17R signaling is required only in nonhematopoietic cells for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Kidney Injury
Share to Adoptive Transfer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bradykinin

Share to Candidemia

Share to Glomerular Basement Membrane

Share to Kidney Tubules

Share to Receptors, Antigen, T-Cell, gamma-delta

Share to Receptors, Interleukin-17

Source

Open in PubMed Open full text

Identifiers

PMID: 29720566
DOI: 10.1172/jci.insight.98241
PMCID: PMC6012520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection.PMID 29720566Read ↗

DIFFERENTIAL EFFECTS OF IL-17 PATHWAY IN DISSEMINATED CANDIDIASIS AND ZYMOSAN-INDUCED MULTIPLE ORGAN FAILURESemantic proximity Read ↗

An essential role of interleukin-17 receptor signaling in the development of autoimmune glomerulonephritisSemantic proximity Read ↗

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.Semantic proximity Read ↗

Cutting Edge: IL-17–Secreting Innate Lymphoid Cells Are Essential for Host Defense against Fungal InfectionSemantic proximity Read ↗

Cutting edge: IL-23 receptor deficiency prevents the development of lupus nephritis in C57BL/6-lpr/lpr mice.Semantic proximity Read ↗

An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogenSemantic proximity Read ↗

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasisSemantic proximity Read ↗

Interleukin 17-Mediated Host Defense against Candida albicansSemantic proximity Read ↗

Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.Semantic proximity Read ↗

Immunity to infection in IL ‐17‐deficient mice and humansSemantic proximity Read ↗

NK1.1- natural killer T cells upregulate interleukin-17 expression in experimental lupus nephritis.Semantic proximity Read ↗

CD137 Signaling is Critical in Fungal Clearance During Systemic <em>Candida albicans</em> InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.