Article
Tissue glucocorticoid resistance/hypersensitivity syndromes.
The Journal of steroid biochemistry and molecular biology - 1 Jun 2003
Kino Tomoshige, De Martino Massimo U, Charmandari Evangelia, Mirani Marco, Chrousos George P
Abstract excerpt
Glucocorticoids have a broad array of life-sustaining functions and play an important role in the therapy of many diseases. Thus, changes of tissue sensitivity to glucocorticoids may be associated with and influence the course and treatment of many pathologic states. Such tissue sensitivity changes may present on either side of an optimal range, respectively as glucocorticoid resistance or hypersensitivity, and...
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