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Article

TRAF4 functions as an intermediate of GITR-induced NF-kappaB activation.

Cellular and molecular life sciences : CMLS - 1 Dec 2004

Esparza E M, Arch R H

Abstract excerpt

Members of the tumor necrosis factor receptor (TNFR) family regulate the activation, differentiation, and function of many cell types, including cells of the immune system. TNFR-associated factors (TRAFs) function as adapter molecules controlling signaling pathways triggered by TNFR family members, such as activation of nuclear factor kappaB (NF-kappaB). Despite intensive research, the function of TRAF4 in...

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Share to Intracellular Signaling Peptides and Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Nerve Growth Factor

Share to TNF Receptor-Associated Factor 2

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Source

Identifiers

PMID: 15583869
DOI: 10.1007/s00018-004-4417-0

Genes

TRAF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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