Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator.

Molecular cell - 7 Oct 2005

Capelson Maya, Corces Victor G

Abstract excerpt

Chromatin insulators are gene regulatory elements implicated in the establishment of independent chromatin domains. The gypsy insulator of D. melanogaster confers its activity through a protein complex that consists of three known components, Su(Hw), Mod(mdg4)2.2, and CP190. We have identified a factor, Drosophila Topoisomerase I-interacting RS protein (dTopors) that interacts with the insulator protein complex...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin
Share to Drosophila melanogaster
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiprotein Complexes

Share to Mutation

Share to Ubiquitin-Protein Ligases

Source

Identifiers

PMID: 16209949
DOI: 10.1016/j.molcel.2005.08.031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator.PMID 16209949Read ↗

Poly(ADP-ribosyl)ation regulates insulator function and intrachromosomal interactions in Drosophila.Semantic proximity Read ↗

RNA interference machinery influences the nuclear organization of a chromatin insulator.Semantic proximity Read ↗

Polycomb and trithorax group proteins mediate the function of a chromatin insulator.Semantic proximity Read ↗

The role of insulators and transcription in 3D chromatin organisation of fliesSemantic proximity Read ↗

The centrosomal protein CP190 is a component of the gypsy chromatin insulator.Semantic proximity Read ↗

A Drosophila insulator interacting protein suppresses enhancer-blocking function and modulates replication timing.Semantic proximity Read ↗

Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells.Semantic proximity Read ↗

Chromatin immunoprecipitation indirect peaks highlight long-range interactions of insulator proteins and Pol II pausing.Semantic proximity Read ↗

Distinct Roles of Chromatin Insulator Proteins in Control of the Drosophila Bithorax Complex.Semantic proximity Read ↗

Nuclear structure and chromosome segregation in Drosophila male meiosis depend on the ubiquitin ligase dTopors.Semantic proximity Read ↗

Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesisSemantic proximity Read ↗

Nuclear lamina structure and meiotic chromosome segregation have different requirements for dTopors-mediated ubiquitination in male Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.