Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Poly(ADP-ribosyl)ation regulates insulator function and intrachromosomal interactions in Drosophila.

Cell - 26 Sept 2013

Ong Chin-Tong, Van Bortle Kevin, Ramos Edward, Corces Victor G

Abstract excerpt

Insulators mediate inter- and intrachromosomal contacts to regulate enhancer-promoter interactions and establish chromosome domains. The mechanisms by which insulator activity can be regulated to orchestrate changes in the function and three-dimensional arrangement of the genome remain elusive. Here, we demonstrate that Drosophila insulator proteins are poly(ADP-ribosyl)ated and that mutation of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Chromosomes, Insect
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Drosophila Proteins

Share to Mutation

Share to Poly(ADP-ribose) Polymerases

Source

Open in PubMed Open full text

Identifiers

PMID: 24055367
DOI: 10.1016/j.cell.2013.08.052
PMCID: PMC3816015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Poly(ADP-ribosyl)ation regulates insulator function and intrachromosomal interactions in Drosophila.PMID 24055367Read ↗

The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator.Semantic proximity Read ↗

Coordinated control of dCTCF and gypsy chromatin insulators in Drosophila.Semantic proximity Read ↗

Mutational analysis of the poly(ADP-ribosyl)ation sites of the transcription factor CTCF provides an insight into the mechanism of its regulation by poly(ADP-ribosyl)ation.Semantic proximity Read ↗

The role of insulators and transcription in 3D chromatin organisation of fliesSemantic proximity Read ↗

Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulationSemantic proximity Read ↗

Functional role of dimerization and CP190 interacting domains of CTCF protein in Drosophila melanogaster.Semantic proximity Read ↗

RNA interference machinery influences the nuclear organization of a chromatin insulator.Semantic proximity Read ↗

Chromatin immunoprecipitation indirect peaks highlight long-range interactions of insulator proteins and Pol II pausing.Semantic proximity Read ↗

Cooperation between architectural C2H2 proteins in CP190 recruitment to Drosophila regulatory elements.Semantic proximity Read ↗

Poly(ADP-Ribose) polymerase 1 (PARP-1) regulates ribosomal biogenesis in Drosophila nucleoli.Semantic proximity Read ↗

The Rtt106 histone chaperone is functionally linked to transcription elongation and is involved in the regulation of spurious transcription from cryptic promoters in yeast.Semantic proximity Read ↗

The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.