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Article

Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells.

Molecular and cellular biology - 1 Nov 2013

Galli Giorgio Giacomo, Carrara Matteo, Francavilla Chiara, de Lichtenberg Kristian Honnens, Olsen Jesper Velgaard, Calogero Raffaele Adolfo, Lund Anders Henrik

Abstract excerpt

PRDM proteins belong to the SET domain protein family, which is involved in the regulation of gene expression. Although few PRDM members possess histone methyltransferase activity, the molecular mechanisms by which the other members exert transcriptional regulation remain to be delineated. In this study, we find that Prdm5 is highly expressed in mouse embryonic stem (mES) cells and exploit this cellular system to...

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Identifiers

PMID: 24043305
DOI: 10.1128/MCB.00545-13
PMCID: PMC3838183

Genes

SET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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