Article
Nuclear structure and chromosome segregation in Drosophila male meiosis depend on the ubiquitin ligase dTopors.
Genetics - 1 Nov 2011
Matsui Maiko, Sharma Krishn C, Cooke Carol, Wakimoto Barbara T, Rasool Mohammad, Hayworth Miranda, Hylton Christopher A, Tomkiel John E
Abstract excerpt
In many organisms, homolog pairing and synapsis at meiotic prophase depend on interactions between chromosomes and the nuclear membrane. Male Drosophila lack synapsis, but nonetheless, their chromosomes closely associate with the nuclear periphery at prophase I. To explore the functional significance of this association, we characterize mutations in nuclear blebber (nbl), a gene required for both spermatocyte...
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