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Article

The centrosomal protein CP190 is a component of the gypsy chromatin insulator.

Molecular cell - 3 Dec 2004

Pai Chi-Yun, Lei Elissa P, Ghosh Dolanchanpa, Corces Victor G

Abstract excerpt

Chromatin insulators, or boundary elements, affect promoter-enhancer interactions and buffer transgenes from position effects. The gypsy insulator of Drosophila is bound by a protein complex with two characterized components, the zinc finger protein Suppressor of Hairy-wing [Su(Hw)] and Mod(mdg4)2.2, which is one of the multiple spliced variants encoded by the modifier of mdg4 [mod(mdg4)] gene. A genetic screen...

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Source

Identifiers

PMID: 15574329
DOI: 10.1016/j.molcel.2004.11.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The centrosomal protein CP190 is a component of the gypsy chromatin insulator.PMID 15574329Read ↗

The role of the Suppressor of Hairy-wing insulator protein in Drosophila oogenesis.Semantic proximity Read ↗

HIPP1 stabilizes the interaction between CP190 and Su(Hw) in the Drosophila insulator complex.Semantic proximity Read ↗

Coordinated control of dCTCF and gypsy chromatin insulators in Drosophila.Semantic proximity Read ↗

Interactions between BTB domain of CP190 and two adjacent regions in Su(Hw) are required for the insulator complex formation.Semantic proximity Read ↗

Multiple interactions are involved in a highly specific association of the Mod(mdg4)-67.2 isoform with the Su(Hw) sites in Drosophila.Semantic proximity Read ↗

A Drosophila insulator interacting protein suppresses enhancer-blocking function and modulates replication timing.Semantic proximity Read ↗

Distinct Roles of Chromatin Insulator Proteins in Control of the Drosophila Bithorax Complex.Semantic proximity Read ↗

EAST affects the activity of Su(Hw) insulators by two different mechanisms in Drosophila melanogaster.Semantic proximity Read ↗

The centrosomal protein CP190 regulates myosin function during early Drosophila development.Semantic proximity Read ↗

The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning.Semantic proximity Read ↗

The gypsy insulator of Drosophila affects chromatin structure in a directional manner.Semantic proximity Read ↗

Investigation of the properties of non-gypsy suppressor of hairy-wing-binding sites.Semantic proximity Read ↗

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