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Article

Distinct Roles of Chromatin Insulator Proteins in Control of the Drosophila Bithorax Complex.

Genetics - 1 Feb 2016

Savitsky Mikhail, Kim Maria, Kravchuk Oksana, Schwartz Yuri B

Abstract excerpt

Chromatin insulators are remarkable regulatory elements that can bring distant genomic sites together and block unscheduled enhancer-promoter communications. Insulators act via associated insulator proteins of two classes: sequence-specific DNA binding factors and "bridging" proteins. The latter are required to mediate interactions between distant insulator elements. Chromatin insulators are critical for correct...

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Identifiers

PMID: 26715665
DOI: 10.1534/genetics.115.179309
PMCID: PMC4788238

Genes

CTCF

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Distinct Roles of Chromatin Insulator Proteins in Control of the Drosophila Bithorax Complex.PMID 26715665Read ↗

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