Article
Dissociation of the hepatic phenotype from HNF4 and HNF1alpha expression.
Bioscience reports - 1 Dec 2004
Bulla Gary A, Kraus David M
Abstract excerpt
Dedifferentiated cells have served as tools to understand the molecular consequences of the loss of tissue-specific pathways. Here we report the characterization of one of these cell lines, M29, which lacks the liver-enriched HNF4-HNF1alpha pathway, in order to determine if this class of variant cell lines could provide additional information regarding requirements for tissue-type expression. We report that...
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