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Article

Liver-enriched transcription factors uncoupled from expression of hepatic functions in hepatoma cell lines.

Molecular and cellular biology - 1 Nov 1997

Chaya D, Fougère-Deschatrette C, Weiss M C

Abstract excerpt

Among the liver-enriched transcription factors identified to date, only expression of hepatocyte nuclear factor 4 (HNF4) and hepatocyte nuclear factor 1 (HNF1) is in strict correlation with hepatic differentiation in cultured rat hepatoma cells. Indeed, differentiated hepatoma cells that stably express an extensive set of adult hepatic functions express liver-enriched transcription factors, while dedifferentiated...

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Identifiers

PMID: 9343392
DOI: 10.1128/MCB.17.11.6311
PMCID: PMC232482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Liver-enriched transcription factors uncoupled from expression of hepatic functions in hepatoma cell lines.PMID 9343392Read ↗

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis.Semantic proximity Read ↗

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