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Article

Genome-wide analysis of hepatic gene silencing in hepatoma cell variants.

Genomics - 1 Sept 2012

Bulla Gary A, Aylmer Caitlin M, Dust Adele L, Kurkewich Jeffrey L, Mire Leon K, Estanda Arnold B

Abstract excerpt

Genome-wide gene expression profiling was carried out on rat hepatoma cells and compared to profiles of hepatoma "variant" cell lines derived via a stringent selection protocol that enriches for rare cells (<1 in 100,000 cells) that fail to drive liver function. Results show 132 genes that are strongly (>5-fold) repressed in each of the four variant cell lines tested. An additional 68 genes were repressed in 3 of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22659237
DOI: 10.1016/j.ygeno.2012.05.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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