Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Constancy of expression of the protein kinase A regulatory subunit R1 alpha in hepatoma cell lines of different phenotypes.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Jan 1994

Faust D M, Boshart M, Imaizumi-Scherrer T, Schütz G, Weiss M C

Abstract excerpt

In somatic hybrids between fibroblast microcells and rat hepatoma cells, tissue-specific extinguisher 1 (TSE1), localized to mouse chromosome 11, extinguishes the expression of tyrosine aminotransferase and phospho(enol)pyruvate carboxykinase. Recently, it was demonstrated that TSE1 corresponds to R1 alpha, a regulatory subunit of protein kinase A. Here, we have analyzed whether R1 alpha could play a role in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Cyclic AMP-Dependent Protein Kinases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Phenotype

Share to Proteins

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 8123592

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Constancy of expression of the protein kinase A regulatory subunit R1 alpha in hepatoma cell lines of different phenotypes.PMID 8123592Read ↗

Extinction of alpha 1-antitrypsin gene expression in somatic cell hybrids: evidence for multiple controls.Semantic proximity Read ↗

Tissue-specific extinguisher loci in the murine genome: a screening study based on a rat/mouse microcell hybrid panel.Semantic proximity Read ↗

Subtractive hybridization cloning of a tissue-specific extinguisher: TSE1 encodes a regulatory subunit of protein kinase A.Semantic proximity Read ↗

Regulation of albumin gene expression in hepatoma cells of fetal phenotype: dominant inhibition of HNF1 function and role of ubiquitous transcription factors.Semantic proximity Read ↗

Identification of polypeptides whose presence correlates with retention or loss of an albumin extinguisher chromosome in rat hepatoma-mouse L cell fibroblast microcell hybrids.Semantic proximity Read ↗

Tissue-specific extinguisher loci in the human genome: a screening study based on random marking and transfer of human chromosomes.Semantic proximity Read ↗

Dissociation of the hepatic phenotype from HNF4 and HNF1alpha expression.Semantic proximity Read ↗

Liver-enriched transcription factors uncoupled from expression of hepatic functions in hepatoma cell lines.Semantic proximity Read ↗

Genetic analysis of a transcriptional activation pathway by using hepatoma cell variants.Semantic proximity Read ↗

Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells.Semantic proximity Read ↗

Expression and localization of hepatocyte domain-specific plasma membrane proteins in hepatoma x fibroblast hybrids and in hepatoma dedifferentiated variants.Semantic proximity Read ↗

Extinction of albumin gene expression in a panel of human chromosome 2 microcell hybrids.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.